DMAE / ESTRIOL / GHK-CU / HYALURONIC ACID BIOPEPTIDE 3% / 0.3% / 0.2% / 1.5%

Description

DMAE / ESTRIOL / GHK-CU / HYALURONIC ACID BIOPEPTIDE 3% / 0.3% / 0.2% / 1.5%

Treatment of skin aging with topical estrogens.

After treatment for 6 months, elasticity and firmness of the skin had markedly improved and the wrinkle depth and pore sizes had decreased by 61 to 100% in both groups. Furthermore, skin moisture had increased and the measurement of wrinkles using skin profilometry, revealed significant, or even highly significant, decreases of wrinkle depth in the estradiol and the estriol groups, respectively. On immunohistochemistry, significant increases of Type III collagen labeling were combined with increased numbers of collagen fibers at the end of the treatment period. As to hormone levels, only those of PRL had increased significantly and no systemic hormonal side effects were noted.

The role of dimethylaminoethanol in cosmetic dermatology.

Mitigation forehead lines and periorbital fine wrinkles, and in improving lip shape and fullness and the overall appearance of aging skin. These effects did not regress during a 2-week cessation of application. Beneficial trends (p > 0.05 but

Hyaluronic acid: A key molecule in skin aging

The key molecule involved in skin moisture is hyaluronic acid (HA) that has a unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association, and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.